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Can You Use Niacinamide With Vitamin C And Retinol?

In the present day scenario, the skincare industry is replete with a wide array of ingredients, some of which have been around for quite some time, and others that are rather new and more fad-like. Amongst these, there are certain skincare ingredients that not only assure scientifically proven effects but have also stood the test of time! Vitamin C and Niacinamide happen to be two such ingredients that have been proven to promote healthy skin and combat hyperpigmentation.

So, if both these ingredients have proven their worth, the question arises, can combining these two in the skincare routine have an even better effect? Well, we are about to find that out. But first, let us take a closer look at each of these powerful ingredients, and understand the role they play in promoting the highly-sought after even skin tone!


Niacinamide, is essentially a form of Vitamin B3 or Niacin. It has been proven to offer numerous benefits for the skin. When applied topically, in the form of a serum, Niacinamide enables the enhanced production of ceramides which improve the skin's barrier function. Moreover, since Niacinamide has anti-inflammatory and antibacterial properties, it also helps in the treatment of acne and other inflammations that result in skin redness and uneven skin tone.

Benefits Of Niacinamide

Even if we tried, we wouldn't be able to encapsulate all the benefits of Niacinamide at once. Hence, let us simply put them in a manner that'd be easier to decipher!

  • It improves the production of keratin, a protein substance that is responsible for keeping the skin firm and healthy
  • It allows the skin to form a ceramide barrier that locks the moisture within the skin.
  • It helps reduce all types of inflammation and is particularly useful in treating acne or other blemishes.
  • It also regulates the production of sebum and protects the skin against sun damage through UV rays that might result in hyperpigmentation.
  • It stimulates collagen production, thereby reducing wrinkles and fine lines

Needless to say, Niacinamide is a must-have ingredient, if you are on the lookout for a holistic skincare treatment!

How to Use Niacinamide?

Well, Chemist At Play’s Pore Minimising Face Serum is all you need to include this astounding component in your skincare regime. While Niacinamide is considered to be one of the most gentle elements, if you have excessively sensitive skin, we recommend getting in touch with a board-certified dermatologist before you introduce it n your skincare regime.

Did You Know?

Wikipedia lists the following as naturally occurring food sources for Niacinamide - meat, fish, nuts, and mushrooms as well as in some vegetables. It is also commonly added to cereals and other foods. Moreover, many multivitamins contain 20–30 mg of vitamin B3.

Can You Use Niacinamide With Vitamin C And Retinol

Vitamin C

We are sure, you must have heard all about the glory of Vitamin C when it comes to skincare products! And why not? After all, there is barely any element that can even compete with this super-ingredient for its potent antioxidant properties and ability to neutralize free radicals. Primarily known for its skin brightening properties, Vitamin C serum also helps in enhancing collagen production, thereby fighting the signs of aging.

Benefits Of Vitamin C

When applied topically, Vitamin C Serum can offer a wide array of benefits including but not limited to -

  • It is known to enhance skin brightness
  • It reduces tan lines on the skin
  • It helps reduce the production of melanin, thereby reducing dark spots and pigmentation
  • It improves skin elasticity and keeps wrinkles and fine lines at bay, thanks to its ability to increase collagen production
  • It helps reduce inflammation, thus promoting an even skin tone


So, yes! All that you have heard or read about the power of pure Vitamin C is absolutely true!

How to Use Vitamin C?

Don't worry, we have got you covered here as well! Simply use the Advance Brightening Face Serum, at least once a day, and unravel the marvelous skin that you have always been waiting for!

You can also consider adding vitamin C to your diet, through foods such as citrus fruits, peppers, strawberries, broccoli, brussels sprouts, and potatoes, or simply use a vitamin c infused moisturizer to keep your skin hydrated and radiant.

Can you use Niacinamide And Vitamin C together?

Now on to the most important subject! Can these two ingredients be used in conjunction! Well, to be frank, YES! You certainly can. Not only are these two ingredients complementary to each other, but they can also ensure that a vast array of your skin problems go away for good! What's even better? Vitamin C and Niacinamide are both gentle on every skin type, rarely leading to any unwanted reaction!

So, yes, you get the best of both worlds, without having to care for any repercussions.

You may be wondering...What about the contracting views you had read about on the same subject? Well, let us clear the air for you. The research that you may have read about was conducted in the 1960s, and hence it is safe to say that it stands outdated. Moreover, the results of the research indicated an interaction wherein pure ascorbic acid and niacinamide in a high-temperature environment reacted to produce nicotinic acid, which in turn caused irritation and redness in the skin. The keyword here is "high-temperature environment".

In the present day scenario, most skincare products use rather stable forms of Vitamin C such as ascorbyl palmitate and magnesium ascorbyl phosphate in place of ascorbic acid, ensuring little to no possibilities of an adverse reaction. Moreover, when stored in a cool, dry place and in absence of extreme environmental aggressors, one can rest assured that these skincare products offer the desired results!

How to Use Niacinamide And Vitamin C together?

Short Answer - Through the regular topical use of the two serums provided in the Brightening Duo by Chemist at Play!

Long Answer - While Vitamin C takes on the responsibility of inhibiting the pigment-producing enzyme tyrosinase, Niacinamide prevents the transfer of pigment within cells. Then again, Vitamin C, being an unstable molecule works better at a low pH, Niacinamide works better at higher pH levels. They both may have different acting mechanisms, but they work towards the same goal - keeping the skin radiant and spot-free!

So, which one to put first. Well, to be truthful, it just doesn't matter. All you need to do is follow the thumb rule - Apply your skincare products beginning from the thinnest going to the thickest. Consequently, a serum would always go before a moisturizer, while an oil (if any) should be applied at last.

Final Thoughts On Niacinamide with Vitamin C and Retinol

Simply put, if bright and radiant skin is your goal, you can and you definitely should use both, Niacinamide and Vitamin C as a part of your skincare routine. Trust us, within a few months your skin will thank you. And within a few years, when your skin shows no signs of aging and is healthy as can be you will thank us! So, wait no more before you choose to save your skin from free radical damage and visible signs of aging by adding this dynamic duo to your range of cosmetics!

Frequently Asked Questions About Niacinamide and Vitamin C:

Should I use Vitamin C or Niacinamide first?

Niacinamide and Vitamin C can be used together with a gap of a few minutes between applications. Here, it rarely matters as to which one you are using first. That said, you can choose to use both of this skin-brightening compounds at different times during the day, and experience the same effects.

Is vitamin C or Niacinamide better for the skin?

Vitamin C is known to inhibit the production of meaning (which is known to cause dark spots), while Niacinamide blocks melanin from transferring within the cells of the skin. Since both these elements function differently, one cannot be said to be better than the other.

Can I use Niacinamide instead of vitamin C?

Niacinamide and Vitamin C have both been proven to be effective in treating skin concerns mainly related to the pigment called melanin. However, since both elements function differently, one can't be used in place of the other. As a matter of fact, combining niacinamide and vitamin c can help achieve the desired results with greater ease.

Which is better Retinol or Niacinamide?

While both compounds have similar benefits for the skin, Retinol is relatively stronger than niacinamide. It is for this reason, that retinol causes irritation, redness, and dry skin in some users. To enjoy the benefits of both, it is recommended to pair the two ingredients. Doing so ensures that Niacinamide helps keep the skin hydrated, thereby reducing the side effects of dryness and irritation caused by retinol.

Can I use Niacinamide serum every day?

Yes, in fact, Niacinamide serum can be easily used twice a day, every day! This is because it can be is well-tolerated by most skin types. Moreover, this skincare ingredient can be worn in almost all seasons and proves to be particularly helpful during the dry winters where it helps keep the skin moisturized.

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